IL-4 Protein

Produktnummer ABIN2830786

Recombinant IL-4-Protein exprimiert in Escherichia coli (E. coli).

Kurzübersicht für IL-4 Protein (ABIN2830786)

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Protein-Typ: Recombinant

Biologische Aktivität: Active

Spezies: Rhesusaffen

Quelle: Escherichia coli (E. coli)

Applikation: Functional Studies (Func)

Reinheit: >96 % as determined by SDS-PAGE and HPLC.

Produktdetails

Sequenz: HNCHIALREI IETLNSLTEQ KTLCTKLTIT DILAASKNTT EKETFCRAAT VLRQFYSHHE KDTRCLGATA QQFHRHKQLI RFLKRLDRNL WGLAGLNSCP VKEANQSTLE DFLERLKTIM REKYSKCSS

Produktmerkmale: Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using human TF-1 cells is less than 1.0 ng/mL, corresponding to a specific activity of ＞ 1.0 x 106 IU/mg.

Sterilität: 0.2 μm filtered

Anwendungsinformationen

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Buffer: 2 x PBS, pH 7.4, 5 % trehalose

Lagerung: -20 °C

Antigendetails

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Andere Bezeichnung: IL4

Hintergrund: Relevance: Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes (By similarity). {ECO:0000250}.
Synonyms: IL-4, BSF-1, Lymphocyte stimulatory factor 1

Molekulargewicht: 14.9 kDa

UniProt: P51492

Pathways: JAK-STAT Signalweg, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation